Dindolyl Methane, or DIM as it’s more commonly referred to, is a very popular supplement used by bodybuilders and others who are interested in increasing the growth of their muscles. Recent research has shown that DIM could pose health risks. For example, DIM can cause serious liver damage when consumed in excess. Another risk is kidney damage, which may result in kidney failure. The long-term health risks associated with DIM have many bodybuilders and athletes think about the question: should I supplement my diet with a supplement with DIM?
Most people use diindolylmethane supplements to boost the production of testosterone. It is known that testosterone functions as an androgen. This means that it can trigger hormonal changes in tissues. DIM has been proven in studies to mimic the effects of testosterone, and other hormones. Certain manufacturers have added diindolylmethane (DIM) to their products to increase their appeal to males since men are more likely to produce testosterone than women. Men will react to products that mimic natural testosterone.
In the end, numerous companies promote DIM as a cancer-fighter. While diindolylmethane has been proven effective in reducing the growth of tumors in laboratory animals it was administered orally to the animals. To achieve the same result in humans, diindolylmethane has to be consumed in large doses for a long period of time. In addition, while the animals tested were cancer free for several years but all of them suffered from liver disease at some point, probably because of the high levels of diindolylmethane in their systems. To have a closer understanding of how DIM is affecting the body, you should consult a physician.
According to the US National Institute of Environmental Health Safety and Security, the only way to prove that DIM is effective in treating breast cancer is to conduct an experiment wherein cells from healthy breast cancer cells are exposed to large doses of diindolylmethane over a prolonged period of time. Like any chemical, there are both pros and cons associated with using it. The advantages include the capability to mimic hormones. This means you can create insulin, which can stop the proliferation of cancer cells. The downside is that diindolylmethane can also produce a potentially damaging chemicals called DMSO. Read more about dim diindolylmethane benefits now.
One of the most common claims for diindolylmethane to be an option for treating different health issues is that it can act as a natural, anti-fungal, antibacterial and anti-cancer agent. These claims were rejected by the National Institute of Health after an exhaustive review of supporting research. According to the Institute of Chemical Technology, there were no studies conducted to verify this assertion. The Institute of Chemical Safety, through an in-depth examination of the safety profile of the firestone concluded that the information presented by pharmaceutical companies about the benefits of diindolylmethane to humans were not completely reliable.
In the May 2021 edition of the Journal of Toxicology and Environmental Health, van der Goes, et al. pointed out numerous potential hazards that could be posed by the use of diindolylmethane, including skin rash, allergic reactions, asthma attacks, dizziness, headaches, and respiratory issues. They also noted that the recommended daily allowance for this chemical is 0.2 milligrams, or about one tenth of one teaspoon. It is unclear what the level of concentration is when it is compounded with other compounds. This substance is not considered safe since it hasn’t been thoroughly examined.
The abstract of the view indicates that the use of diindolylmethane (DIEM) in the context of treating cancer is based on the idea of inhibiting the intracellular inhibition of pyruvate metabolite through flavenoids, and thereby preventing accumulation of oxalates in renal tubule cells as well as adenine granulocytes. Metabiplicate toxicology studies on the drug have not demonstrated that this chemical can cause overdose. In June 1996, the Food and Drug Administration approved the drug as a prescription drug. According to the FDA the company that makes firestone Tincture is in the process of completing two major tests in Europe and the United States.
The view abstract also shows that diindolylmethane’s usage in cancer treatment is based on the idea of inhibiting intracellular inhibition by flavenoids of pyruvate metabolism and thus hindering the accumulation of oxalates and adenine in renal tubule cells. The drug metabiplicate toxicology studies have not demonstrated that this chemical could cause overdose. The Food and Drug Administration approved the substance as a prescription drug in June 1996. According to the FDA the company that makes firestone Tincture is currently completing two major trials in Europe and the United States. According to FDA, the FDA states that the manufacturer of firestone Tincture is completing two major trials in Europe and one in the United States.